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Meconium is the earliest stool of a mammalian infant resulting from defecation.Unlike later feces, meconium is composed of materials ingested during the time the infant spends in the uterus: intestinal epithelial cells, lanugo, mucus, amniotic fluid, bile, and water.
[26] [27] In infants, HSCR typically presents when a newborn is unable to pass the first feces, or meconium within 48 hours of birth. [26] Other symptoms include blockage of the intestine, fever, rapid release of stool and flatulence upon rectal examination, and may present with diarrhea in infants. [26] [27]
Neonatal bowel obstruction is grouped into two general categories: high, or proximal, obstruction and low, or distal obstruction, both of which are suspected by failure to pass meconium at birth. High obstruction can be suspected based on the double bubble sign .
The time taken for food to transit through the gastrointestinal tract varies on multiple factors, including age, ethnicity, and gender. [ 28 ] [ 29 ] Several techniques have been used to measure transit time, including radiography following a barium -labeled meal, breath hydrogen analysis, scintigraphic analysis following a radiolabeled meal ...
Manifestations: When the newborn cries, there is a reversal of blood flow through the foramen ovale which causes the newborn to appear mildly cyanotic in the first few days of life. The heart rate of the newborn should be between 110 and 160 beats per minute and it is common for the heart rate to be irregular in the first few hours following birth.
This enables normal peristalsis instead of abnormal contraction and retrograde movement of bowel contents. [16] Researchers demonstrated that patients who had positive results with biofeedback had evidence of improved autonomic innervation of the colon, increased colonic transit time, and had increased quality of life scores. [16]
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Meconium aspiration syndrome (MAS), also known as neonatal aspiration of meconium, is a medical condition affecting newborn infants. It describes the spectrum of disorders and pathophysiology of newborns born in meconium-stained amniotic fluid (MSAF) and have meconium within their lungs. Therefore, MAS has a wide range of severity depending on ...