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The tunica intima (Neo-Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells (and macrophages in areas of disturbed blood flow), [1] [2] and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow.
The tunica media is made up of smooth muscle cells, elastic tissue and collagen.It lies between the tunica intima on the inside and the tunica externa on the outside.. The middle coat (tunica media) is distinguished from the inner (tunica intima) by its color and by the transverse arrangement of its fibers.
The inner layer, tunica intima, is the thinnest layer. It is a single layer of flat cells (simple squamous epithelium) glued by a polysaccharide intercellular matrix, surrounded by a thin layer of subendothelial connective tissue interlaced with a number of circularly arranged elastic bands called the internal elastic lamina. A thin membrane of ...
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Micrograph showing the internal elastic lamina (thin pink wavy line - image edge mid-left to image edge bottom-centre-left). H&E stain.. The internal elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of blood vessels.
The structure of the vasa vasorum varies with the size, function and location of the vessels. Cells need to be within a few cell-widths of a capillary to stay alive. In the largest vessels, the vasa vasorum penetrates the outer (tunica adventitia) layer and middle (tunica media) layer almost to the inner (tunica intima) layer.
Inside this layer is the tunica media, which is made up of smooth muscle cells, elastic tissue (also called connective tissue proper) and collagen fibres. [3] The innermost layer, which is in direct contact with the flow of blood, is the tunica intima. The elastic tissue allows the artery to bend and fit through places in the body.
Tunica muscularis refers to muscular layers in the walls of hollow organs such as the gut, where they are required for peristalsis, and sometimes for sphincters. [7] Tunica serosa is the serous membrane [7] Tunica vaginalis is the serous covering of the testis within the scrotum. [6] Tunica vasculosa could refer