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The cornea is the transparent front part of the eyeball which covers the iris, pupil, and anterior chamber.Along with the anterior chamber and lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power.
The corneal epithelium (epithelium corneae anterior layer) is made up of epithelial tissue and covers the front of the cornea. It acts as a barrier to protect the cornea, resisting the free flow of fluids from the tears, and prevents bacteria from entering the epithelium and corneal stroma.
At its centre, a human corneal stroma is composed of about 200 flattened lamellae (layers of collagen fibrils), superimposed one on another. [1] They are each about 1.5-2.5 μm in thickness. The anterior lamellae interweave more than posterior lamellae.
The corneal endothelium is a single layer of endothelial cells on the inner surface of the cornea. It faces the chamber formed between the cornea and the iris. The corneal endothelium are specialized, flattened, mitochondria-rich cells that line the posterior surface of the cornea and face the anterior chamber of the eye. The corneal ...
The trabecular meshwork is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea).
Copper disposition on corneal Descemet's membrane. Significant damage to the membrane may require a corneal transplant. Damage caused by the hereditary condition known as Fuchs dystrophy (q.v.)—where Descemet's membrane progressively fails and the cornea thickens and clouds because the exchange of nutrients/fluids between the cornea and the rest of the eye is interrupted—can be reversed by ...
The function of the Bowman's layer remains unclear and it appears to have no critical function in corneal physiology. [3] Recently, it is postulated that the layer may act as a physical barrier to protect the subepithelial nerve plexus and thereby hastens epithelial innervation and sensory recovery.
The corneal limbus also contains vessels that aid in the transport of nutrients and cytokines, making the peripheral cornea more susceptible to immune-mediated inflammation than the center. [5] The cornea refracts incoming light to ensure focusing of light onto the retina, is covered by a tear film (anterior), and boarders the aqueous filled ...