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Current recommendations for the treatment of leprosy suggest multidrug regimens rather than monotherapy because such a regimen has proven to be more effective, delays the emergence of resistance, prevents relapse, and shortens the duration of therapy. Established agents used in the treatment of leprosy are dapsone, clofazimine, and rifampicin ...
Leprosy has historically been associated with social stigma, which continues to be a barrier to self-reporting and early treatment. [4] Leprosy is classified as a neglected tropical disease. [20] World Leprosy Day was started in 1954 to draw awareness to those affected by leprosy. [21] [4] The study of leprosy and its treatment is known as ...
Dapsone is the recommended treatment for erythema elevatum diutinum, as a review found that using oral dapsone alone was effective in 80% of early cases of the disease. However, dapsone can potentially cause severe side effects, meaning that sometimes steroids or other antibiotics should be used instead, although these alternative treatments ...
Clofazimine, sold under the brand name Lamprene, is a medication used together with rifampicin and dapsone to treat leprosy. [1] It is specifically used for multibacillary (MB) leprosy and erythema nodosum leprosum. [2]
MDT is used to treat leprosy because treatment of leprosy with one drug (monotherapy) can result in drug resistance. The drug combination used in MDT will depend on the classification of the disease. WHO recommends patients with multibacillary leprosy use a combination of Rifampicin, Clofazimine, and Dapsone for 12 months.
Promin, or sodium glucosulfone is a sulfone drug that was investigated for the treatment of malaria, [1] tuberculosis [2] and leprosy. [3] [4] It is broken down in the body to dapsone, which is the therapeutic form. [5]
However, with fewer patients in the hospital and medical advances for the treatment of leprosy, the leprosarium lost funding and subsequently shut down in 1999. [13] Out-patient care in several clinics around the United States supply primary treatment and medication to the 200 or so new cases diagnosed yearly in the US.
Hydnocarpus wightiana seed oil has been widely used in traditional Indian medicine, especially in Ayurveda, and in Chinese traditional medicine for the treatment of leprosy. It entered early Western medicine in the nineteenth century before the era of sulfonamides and other antibiotics for the treatment of several skin diseases and leprosy. [2]
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