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Virtually all infections with rabies resulted in death until two French scientists, Louis Pasteur and Émile Roux, developed the first rabies vaccination in 1885. Nine-year-old Joseph Meister (1876–1940), who had been mauled by a rabid dog, was the first human to receive this vaccine. [30]
Joseph Meister in 1885. Joseph Meister (21 February 1876 – 24 June 1940) was the first person to be inoculated against rabies by Louis Pasteur, and likely the first person to be successfully treated for the infection, which has a >99% fatality rate once symptoms set in.
1885 – First vaccine for rabies by Louis Pasteur and Émile Roux [5] [6] 1890 – First vaccine for tetanus (serum antitoxin) by Emil von Behring [7] 1896 – First vaccine for typhoid fever by Almroth Edward Wright, Richard Pfeiffer, and Wilhelm Kolle [8] 1897 – First vaccine for bubonic plague by Waldemar Haffkine
The treatment's success laid the foundations for the manufacture of many other vaccines. The first of the Pasteur Institutes was also built on the basis of this achievement. [55] In The Story of San Michele, Axel Munthe writes of some risks Pasteur undertook in the rabies vaccine research: [132] Pasteur himself was absolutely fearless.
Amid anthrax vaccine's success, Pasteur introduced rabies vaccine (1885), the first human vaccine since Jenner's smallpox vaccine (1796). On 6 July 1885, the vaccine was tested on 9-year old Joseph Meister who had been bitten by a rabid dog but failed to develop rabies, and Pasteur was called a hero. [13] (Even without vaccination, not everyone ...
Given their many differences, they clashed often as they worked towards vaccines against anthrax and rabies. The main issues between Roux and Pasteur regarded the ethics of human experimentation, specifically, the amount of evidence from animal experimentation needed in order to justify giving the rabies vaccine to humans. Roux was more ...
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The first written record of rabies is in the Mesopotamian Codex of Eshnunna (c. 1930 BC), which dictates that the owner of a dog showing symptoms of rabies should take preventive measures against bites. If another person were bitten by a rabid dog and later died, the owner was heavily fined.
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