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The size of either C4A or C4B gene can be 21 kb (long, L) or 14.6 kb (short, S). Also, the long C4 gene uniquely contains a retrovirus HERV-K(C4) in its intron 9 that imposes transcription of an extra 6.36 kb, hence the “longer” string of gene. [2] [14] Thus, C4 genes have a complex pattern of variation in gene size, copy number, and ...
Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. [ 5 ] This gene encodes the basic form of complement factor 4, part of the classical activation pathway.
The number of fat cells is difficult to decrease through dietary intervention, though some evidence suggests that the number of fat cells can decrease if weight loss is maintained for a sufficiently long period of time (>1 year; though it is extremely difficult for people with larger and more numerous fat cells to maintain weight loss for that ...
The cleaved products attract phagocytes to the site of infection and tags target cells for elimination by phagocytosis. In addition, the C5 convertase initiates the terminal phase of the complement system, leading to the assembly of the membrane attack complex . The membrane attack complex creates a pore on the target cell's membrane, inducing ...
Set point theory can be construed as implying weight regulation in a wide or tight range around the set point, in a symmetric or in an asymmetric manner (i.e. treating weight gain and loss either the same or differently), and may apply to regulation of body fat levels specifically (in a multi-compartment model) or to overall body weight.
Red blood cells have an average volume of 80–100 femtoliters, but individual cell volumes vary even in healthy blood. [1] Certain disorders, however, cause a significantly increased variation in cell size. Higher RDW values indicate greater variation in size. Normal reference range of RDW-CV in human red blood cells is 11.5–15.4%.
13137 Ensembl ENSG00000196352 ENSMUSG00000026401 UniProt P08174 Q61476 RefSeq (mRNA) NM_000574 NM_001114543 NM_001114544 NM_001114752 NM_001300902 NM_001300903 NM_001300904 NM_007827 NM_001317361 RefSeq (protein) NP_000565 NP_001108224 NP_001287831 NP_001287832 NP_001287833 NP_001304290 NP_031853 NP_001391877 Location (UCSC) Chr 1: 207.32 – 207.39 Mb Chr 1: 130.32 – 130.35 Mb PubMed search ...
Retatrutide (LY-3437943) is an experimental drug for obesity developed by American pharmaceutical company Eli Lilly and Company.It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors). [1]
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