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Fecal calprotectin, a marker of colon inflammation, may be elevated. Computed tomography of the abdomen is not routinely necessary, but may show thickening or inflammation in the distal colon (sigmoid colon) with associated diverticulosis. Treatment may consist of antibiotics, aminosalicylates (mesalamine), or prednisone. In rare cases, surgery ...
Colonic wall structure – points of blood vessel entry in the colonic wall are weaker and more prone to mucosal herniation. Fiber intake – although it is widely believed that low fiber diet is associated with diverticulosis and diverticular disease, recent studies have not confirmed the association but has shown that increased fiber intake ...
Diverticulitis; Other names: Colonic diverticulitis: Section of the large bowel (sigmoid colon) showing multiple pouches (diverticula).The diverticula appear on either side of the longitudinal muscle bundle (taenium), which runs horizontally across the specimen in an arc.
Diverticulosis is the condition of having multiple pouches (diverticula) in the colon that are not inflamed. These are outpockets of the colonic mucosa and submucosa through weaknesses of muscle layers in the colon wall. [1] Diverticula do not cause symptoms in most people. [2]
The sigmoid colon is completely surrounded by peritoneum (and thus is not retroperitoneal), which forms a mesentery (sigmoid mesocolon), which diminishes in length from the center toward the ends of the loop, where it disappears, so that the loop is fixed at its junctions with the iliac colon and rectum, but enjoys a considerable range of movement in its central portion.
Biopsy of the colon is another beneficial test but is more invasive. Other forms of colitis that may present similarly include radiation and diversion colitis. Radiation colitis occurs after irradiation and often affects the rectum or sigmoid colon, similar to ulcerative colitis.
Focal, irregular and asymmetrical gastrointestinal wall thickening on CT scan suggests a malignancy. [9] Segmental or diffuse gastrointestinal wall thickening is most often due to ischemic, inflammatory or infectious disease. [9] Though less common, medications such as ACE inhibitors can cause angioedema and small bowel thickening. [10]
A human colon is considered abnormally enlarged if it has a diameter greater than 12 cm [3] in the cecum (it is usually less than 9 cm [4]), greater than 6.5 cm [3] in the rectosigmoid region and greater than 8 cm [3] for the ascending colon. The transverse colon is usually less than 6 cm in diameter. [4] A megacolon can be either acute or ...