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The neutral theory assumes that most mutations that are not deleterious are neutral rather than beneficial. Because only a fraction of gametes are sampled in each generation of a species, the neutral theory suggests that a mutant allele can arise within a population and reach fixation by chance, rather than by selective advantage. [1]
The Neutral Theory of Molecular Evolution is an influential monograph written in 1983 by Japanese evolutionary biologist Motoo Kimura.While the neutral theory of molecular evolution existed since his article in 1968, [1] Kimura felt the need to write a monograph with up-to-date information and evidences showing the importance of his theory in evolution.
The neutral theory of molecular evolution, proposed by Motoo Kimura in 1968, holds that at the molecular level most evolutionary changes and most of the variation within and between species is not caused by natural selection but by genetic drift of mutant alleles that are neutral.
[3] [1] The surprisingly large amount of molecular divergence within and between species inspired the neutral theory of molecular evolution in the late 1960s. [4] [5] [6] Neutral theory also provided a theoretical basis for the molecular clock, although this is not needed for the clock's validity.
Neutral theory – Theory of evolution by changes at the molecular level; Shifting balance theory – One version of the theory of evolution; Price equation – Description of how a trait or gene changes in frequency over time; Coefficient of relationship – Mathematical guess about inbreeding; Fitness – Expected reproductive success
The neutral theory of molecular evolution assumes that most new mutations are either deleterious (and quickly purged by selection) or else neutral, with very few being adaptive. It also assumes that the behavior of neutral allele frequencies can be described by the mathematics of genetic drift.
According to Axe, the research he provides with his book disproves Darwin's theory of evolution, revealing "a gaping hole has been at its center from the beginning." Click through 10 books that ...
Neutral mutation has become a part of the neutral theory of molecular evolution, proposed in the 1960s. This theory suggests that neutral mutations are responsible for a large portion of DNA sequence changes in a species. For example, bovine and human insulin, while differing in amino acid sequence are still able to perform the same function ...