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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Doxylamine succinate is the active ingredient in many over-the-counter sleep aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
While pyridoxine/doxylamine, a combination of vitamin B 6 and doxylamine, is effective in nausea and vomiting of pregnancy, [48] some have questioned its effectiveness in HG. [49] Ondansetron may be beneficial, however, there are some concerns regarding an association with cleft palate, [50] and there is little high-quality data. [46]
A woman with lower levels in her blood outside of pregnancy may be at a higher risk of developing severe morning sickness in pregnancy, known as HG, researchers said. HG can lead to prolonged ...
Morning sickness affects about 70–80% of all pregnant women to some extent. [4] [5] About 60% of women experience vomiting. [2] Hyperemesis gravidarum occurs in about 1.6% of pregnancies. [1] Morning sickness can negatively affect quality of life, result in decreased ability to work while pregnant, and result in health-care expenses. [3]
Nausea can be caused by weight loss drugs, pregnancy, food poisoning, migraines. Doctors share home remedies for nausea, including ginger and peppermint.
In a breakthrough discovery, scientists have identified the cause of pregnancy morning sickness, raising hope for a possible cure. Researchers found that a hormone exposed to pregnant women ...
Although described as "morning sickness," pregnant women can experience this nausea any time of day or night. The exact cause of morning sickness remains unknown. Nausea and vomiting in pregnancy is typically mild and self-limited, resolving on its own by the 14th week of pregnancy. Other causes should also be ruled out when considering treatment.
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