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[84] [85] There is 29–42% increase in congenital heart defects among children whose mothers were prescribed sertraline during pregnancy, [14] [15] with sertraline use in the first trimester associated with 2.7-fold increase in septal heart defects. [14] Abrupt interruption of sertraline treatment may result in withdrawal or discontinuation ...
Antidepressants are most commonly prescribed for people who have major depressive disorder (MDD). MDD is described as feeling depressed, moody or sad all, every day, for at least two weeks.
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration. [1] Both prescription drugs and over-the-counter drugs (OTCs) can be used in off-label ways, although most studies of off-label use focus on prescription drugs.
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Popular Over-the-Counter Antidepressant Alternatives. So yes, there are big differences between antidepressants and over-the-counter meds. However, some people definitely think they benefit from ...
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into the ...
Lithium is approved by the FDA for the treatment of bipolar disorder and is widely prescribed off-label as a treatment for major depressive disorder, [12] often as an augmentation agent. Lithium is recommended for the treatment of schizophrenic disorders only after other antipsychotics have failed; it has limited effectiveness when used alone. [13]