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Budesonide/formoterol, sold under the brand name Symbicort among others, is a fixed-dose combination medication used in the management of asthma or chronic obstructive pulmonary disease (COPD). [2] It contains budesonide, a steroid; and formoterol, a long-acting β2-agonist (LABA). [2]
An inhaler (puffer, asthma pump or allergy spray) is a medical device used for delivering medicines into the lungs through the work of a person's breathing. This allows medicines to be delivered to and absorbed in the lungs, which provides the ability for targeted medical treatment to this specific region of the body, as well as a reduction in the side effects of oral medications.
Findings indicate that β 2 stimulants, especially in parenteral administration such as inhalation or injection, can induce adverse effects: Tachycardia secondary to peripheral vasodilation and cardiac stimulation (Such tachycardia may be accompanied by palpitations.) [4] Tremor, excessive sweating, anxiety, insomnia, and agitation [5]
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[1] [2] Short-acting β2-adrenergic agonists can be delivered by different devices, for example, nebulizers and metered-dose inhalers. [2] β2-adrenergic agonists can trigger the activation of Gs protein-coupled β2-adrenergic receptors on the airway smooth muscle cells in the lungs.
[1] [2] It is a combination of salbutamol sulfate (albuterol sulfate), a short-acting beta2-adrenergic agonist, and budesonide, an inhaled corticosteroid. [1] [2] It is inhaled using a pressurized metered-dose inhaler. [1] [2] The most common side effects include headache, oral candidiasis, cough, and difficulty speaking. [2]
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