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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Doxylamine succinate is the active ingredient in many over-the-counter sleep aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Vomiting is a common condition affecting about 50% of pregnant women, with another 25% having nausea. [53] However, the incidence of HG is only 0.3–1.5%. [4] After preterm labor, hyperemesis gravidarum is the second most common reason for hospital admission during the first half of pregnancy. [16]
Antihistamines during pregnancy have not been linked to birth defects; however, further research is necessary for some antihistamine medications to determine safety during pregnancy. [56] It is suggested that women speak to their healthcare professionals before taking any over-the-counter or prescription medication while pregnant to ensure that ...
During pregnancy, the body’s immune system is naturally suppressed as “a mechanism for the body to prevent the body from rejecting the fetus,” says Liz Weinandy, MPH, RDN, LD, a registered ...
Pyridoxine (PN) [4] is a form of vitamin B 6 found commonly in food and used as a dietary supplement.As a supplement it is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning. [5]
Acetaminophen has long been considered safe to help reduce fever and relieve pain while pregnant. Here's what experts say about new claims.
Experts say that metformin and insulin can also be used together to help women with type 2 diabetes and gestational diabetes manage blood glucose levels during pregnancy. Metformin is just as safe ...
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