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The sympathetic effects of norepinephrine include: In the eyes, an increase in the production of tears, making the eyes more moist, [19] and pupil dilation through contraction of the iris dilator. In the heart, an increase in the amount of blood pumped. [20] In brown adipose tissue, an increase in calories burned to generate body heat ...
Norepinephrine Epinephrine. A norepinephrine reuptake inhibitor (NRI, NERI) or noradrenaline reuptake inhibitor or adrenergic reuptake inhibitor (ARI), is a type of drug that acts as a reuptake inhibitor for the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET).
Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
Over-the-counter weight loss supplements are unlikely to be the magic pill for weight loss some claim to be. But there are other weight loss treatments with more scientific backing. Here are some ...
Kapex is a weight loss supplement specifically formulated to support those on keto and other low-carb diets. The blend of powerful ingredients is designed to optimize digestion, support muscle ...
Bupropion is a reuptake inhibitor of both norepinephrine and dopamine, and a nicotinic acetylcholine receptor antagonist, and it activates proopiomelanocortin (POMC) neurons in the hypothalamus which give an effect downstream, resulting in loss of appetite and increased energy output.
Products in the works at various pharmaceutical companies aim to make ketamine and other dissociative drugs, such as psychedelics like MDMA, even better antidepressants. Some drugs combine ...
Elevation of norepinephrine levels can sometimes cause anxiety, mildly elevated pulse, and elevated blood pressure. However, norepinephrine-selective antidepressants, such as reboxetine and desipramine, have successfully treated anxiety disorders. [70] People at risk for hypertension and heart disease should monitor their blood pressure.
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