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Common adverse effects include diarrhea, nausea, and abdominal pain. [16] It has a small risk of causing low blood sugar. [16] High blood lactic acid level is a concern if the medication is used in overly large doses or prescribed in people with severe kidney problems. [23] [24] Metformin is a biguanide anti-hyperglycemic agent. [16]
For cancer patients, the harsh side effects of powerful drugs have long been the trade-off for living longer. Jill Feldman, 54, of Deerfield, Illinois, has lived 15 years with lung cancer, thanks ...
Some researchers are investigating how metformin, a common drug used to treat diabetes, may help prolong healthspan and lifespan. What evidence is there to support this notion?
Marksans Pharma Limited has recalled metformin hydrochloride extended-release tablets due to their excessive levels of NDMA, a “probable human carcinogen,” noted the Food and Drug ...
It is generally prescribed at initial diagnosis in conjunction with exercise and weight loss, as opposed to the past, where it was prescribed after diet and exercise had failed. There is an immediate-release as well as an extended-release formulation, typically reserved for patients experiencing gastrointestinal side-effects. It is also ...
In UK the British National Formulary, de facto official prescribing guide, not only describes use of Metformin for PCOS but also suggests dosages to be used (whilst the BNF then notes "Metformin doses in the BNF may differ from those in the product literature" - UK doctors would cite the BNF as a responsible body of opinion on safe prescribing ...
While metformin is only FDA-approved for the treatment of type 2 diabetes mellitus, some healthcare providers prescribe it off-label (meaning, for a purpose other than what it’s FDA-approved to ...
A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...
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