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  2. Bromelain (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Bromelain_(pharmacology)

    The bromelain gel is contraindicated in persons allergic to pineapple or the enzyme papain. [3] The most common side-effects are fever (19% of patients in studies) and local pain (3.6%). Wound infections occur no more frequently than under standard treatment. [3]

  3. Bromelain - Wikipedia

    en.wikipedia.org/wiki/Bromelain

    Bromelain extract is a mixture of protein-digesting (proteolytic) enzymes and several other substances in smaller quantities. The proteolytic enzymes are sulfhydryl proteases; a free sulfhydryl group of a cysteine amino acid side chain is required for function. The two main enzymes are: Stem bromelain – EC 3.4.22.32; Fruit bromelain – EC 3 ...

  4. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    A group of enzymes located in the endoplasmic reticulum, known as cytochrome P-450, is the most important family of metabolizing enzymes in the liver. Cytochrome P-450 is not a single enzyme, but rather consists of a closely related family of 50 isoforms; six of them metabolize 90% of drugs.

  5. First pass effect - Wikipedia

    en.wikipedia.org/wiki/First_pass_effect

    First-pass metabolism may occur in the liver (for propranolol, lidocaine, clomethiazole, and nitroglycerin) or in the gut (for benzylpenicillin and insulin). [4] The four primary systems that affect the first pass effect of a drug are the enzymes of the gastrointestinal lumen, [5] gastrointestinal wall enzymes, [6] [7] [8] bacterial enzymes [5] and hepatic enzymes.

  6. Pineapple cake - Wikipedia

    en.wikipedia.org/wiki/Pineapple_cake

    Contemporary pineapple cake bakeries have created variations on the traditional pineapple cake. The filling may also incorporate preserved egg yolks or other dried fruits such as cranberries or strawberries. [12] Bakeries may also add winter melon to the pineapple jam. This practice was initially an effort to make the tart pineapple filling ...

  7. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    Liver function tests (LFTs or LFs), also referred to as a hepatic panel or liver panel, are groups of blood tests that provide information about the state of a patient's liver. [1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin , bilirubin (direct and indirect), and others.

  8. Hepatic lipase - Wikipedia

    en.wikipedia.org/wiki/Hepatic_lipase

    The activation of HL occurs in two steps. First, HDL that makes its way to the liver, binds to HL thereby removing the heparan sulfate proteoglycan and freeing up the hepatic lipase into the bloodstream, but HL is still inactive due to the proteins on the surface of the lipoprotein. Second, HDL unbinds from HL to activate HL enzymes in the ...

  9. Butyrylcholinesterase - Wikipedia

    en.wikipedia.org/wiki/Butyrylcholinesterase

    Butyrylcholinesterase (HGNC symbol BCHE; EC 3.1.1.8), also known as BChE, BuChE, BuChase, pseudocholinesterase, or plasma (cholin)esterase, [5] is a nonspecific cholinesterase enzyme that hydrolyses many different choline-based esters. In humans, it is made in the liver, found mainly in blood plasma, and encoded by the BCHE gene. [6]