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Coenzymes Q is a coenzymefamily that is ubiquitousin animals and many Pseudomonadota,[13]a group of gram-negative bacteria. The fact that the coenzyme is ubiquitous gives the origin of its other name, ubiquinone. [1][2][14]In humans, the most common form of coenzymes Q is coenzyme Q10, also called CoQ10(/ˌkoʊkjuːˈtɛn/) or ubiquinone-10.
Haptoglobin (abbreviated as Hp) is the protein that in humans is encoded by the HP gene. [5][6] In blood plasma, haptoglobin binds with high affinity to free hemoglobin [7] released from erythrocytes, and thereby inhibits its deleterious oxidative activity. Compared to Hp, hemopexin binds to free heme. [8]
[7] [18] [28] Early signs of systemic complement-mediated TMA include thrombocytopenia (platelet count below 150,000 or a decrease from baseline of at least 25%) [16] and evidence of microangiopathic hemolysis, which is characterized by elevated LDH levels, decreased haptoglobin, decreased hemoglobin, and/or the presence of schistocytes.
Symptoms of hemolytic anemia are similar to the general signs of anemia.[2] General signs and symptoms include fatigue, pallor, shortness of breath, and tachycardia.[2] In small children, failure to thrivemay occur in any form of anemia. [6][7]In addition, symptoms related to hemolysis may be present such as chills, jaundice, dark urine, and an ...
Type of jaundice. Hemolytic jaundice, also known as prehepatic jaundice, is a type of jaundicearising from hemolysisor excessive destruction of red blood cells, when the byproduct bilirubinis not excreted by the hepaticcells quickly enough.[1] Unless the patient is concurrently affected by hepatic dysfunctions or is experiencing hepatocellular ...
Cabergoline, sold under the brand name Dostinex among others, is a dopaminergic medication used in the treatment of high prolactin levels, prolactinomas, Parkinson's disease, and for other indications. [2] It is taken by mouth. Cabergoline is an ergot derivative and a potent dopamine D 2 receptor agonist.
Phenprocoumon (marketed under the brand names Marcoumar, Marcumar and Falithrom) is a long-acting blood thinner drug to be taken by mouth, and a coumarin derivative. [ 2 ] It acts as a vitamin K antagonist and inhibits blood clotting (coagulation) by blocking synthesis of coagulation factors II, VII, IX and X.
Hyoscine butylbromide. Hyoscine butylbromide, also known as scopolamine butylbromide[4] and sold under the brandname Buscopan among others, [5] is an anticholinergic medication used to treat abdominal pain, esophageal spasms, bladder spasms, biliary colic, [6] and renal colic. [7][8] It is also used to improve excessive respiratory secretions ...