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MRI contrast agents are contrast agents used to improve the visibility of internal body structures in magnetic ... the dose can be as low as 0.1 mmol/kg of body ...
Gadobutrol contrast media is a clear, colorless-to-pale yellow solution of 1 mmol/mL formulation, available in single dose vials (2 mL, 7.5 mL, 10mL, and 15 mL), single dose pre-filled injections (7.5 mL, 10 mL, 15 mL), and pharmacy bulk packages (30 mL and 65 mL) containing multiple vials. [19]
Gadodiamide is a contrast medium used for cranial and spinal magnetic resonance imaging (MRI) and for general MRI of the body after intravenous administration. It provides contrast enhancement and facilitates visualisation of abnormal structures or lesions in various parts of the body including the central nervous system (CNS).
Gadopiclenol was approved for medical use in the United States in September 2022 by the Food and Drug Administration. [2] [12]In October 2023, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion, recommending the granting of a marketing authorization for the medicinal product Elucirem, intended for contrast-enhanced ...
Gadoteric acid, sold under the brand name Dotarem among others, is a macrocycle-structured gadolinium-based MRI contrast agent (GBCA).It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd 3+), and is used in form of the meglumine salt (gadoterate meglumine).
In the form of the methylglucamine salt meglumine gadobenate or gadobenate dimeglumine , it is used as a gadolinium-based MRI contrast medium. [4] BOPTA is a derivative of DTPA in which one terminal carboxyl group, –C(O)OH is replaced by -C–O–CH 2 C 6 H 5. Thus gadobenic acid is closely related to gadopentetic acid.
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Gadopentetic acid, sold under the brand name Magnevist, is a gadolinium-based MRI contrast agent. [2]It is usually administered as a salt of a complex of gadolinium with DTPA (diethylenetriaminepentacetate) with the chemical formula A 2 [Gd(DTPA)(H 2 O)]; when cation A is the protonated form of the amino sugar meglumine the salt goes under the name "gadopentetate dimeglumine".