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Test Sensitivity and specificity Approximate peak Description Troponin test: The most sensitive and specific test for myocardial damage. Because it has increased specificity compared with CK-MB, troponin is composed of 3 proteins- Troponin C, Cardic troponin I, and Cardiac troponin T. Troponin I especially has a high affinity for myocardial injury.
They are measured in the blood to differentiate between unstable angina and myocardial infarction (heart attack) in people with chest pain or acute coronary syndrome. A person who recently had a myocardial infarction has areas of damaged heart muscle and elevated cardiac troponin levels in the blood. [15]
It is a useful marker in the laboratory diagnosis of heart attack. [2] It occurs in different plasma concentration but the same circumstances as troponin T - either test can be performed for confirmation of cardiac muscle damage and laboratories usually offer one test or the other. [3]
When her tests returned, doctors noticed Hutt experienced heightened levels of troponin, a protein in the heart muscle’s cells, according to the National Library of Medicine. Elevated troponin ...
When she arrived at the emergency room, staff ran a variety of tests, including a blood test that showed that she had troponin in her blood, which indicates someone had a heart attack, says the ...
[13] [14] Many tests are helpful with diagnosis, including electrocardiograms (ECGs), blood tests and coronary angiography. [7] An ECG, which is a recording of the heart's electrical activity, may confirm an ST elevation MI , if ST elevation is present. [8] [15] Commonly used blood tests include troponin and less often creatine kinase MB. [7]
Three blood biomarkers could help predict heart attack and stroke risk in women. Image credit: Angela Lumsden/ Stocksy . Cardiovascular disease is the leading cause of death in women globally.
Troponin T binds to tropomyosin and helps position it on actin, [2] and together with the rest of the troponin complex, modulates contraction of striated muscle. [3] The cardiac subtype of troponin T is especially useful in the laboratory diagnosis of heart attack because it is released into the blood-stream when damage to heart muscle occurs. [4]
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