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  2. Thyroid disease in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease_in_pregnancy

    Thyroid hormone concentrations in blood are increased in pregnancy, partly due to the high levels of estrogen and due to the weak thyroid stimulating effects of human chorionic gonadotropin (hCG) that acts like TSH. Thyroxine (T4) levels rise from about 6–12 weeks, and peak by mid-gestation; reverse changes are seen with TSH.

  3. Maternal hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Maternal_Hypothyroidism

    Thyroid hormones, T4 and TSH, diffuse across the placenta traveling from the mother to fetus for 10–12 weeks before the fetus’s own thyroid gland can begin synthesizing its own thyroid hormones. [2] The mother continues to supply some T4 to the fetus even after he/she is able to synthesize his/her own.

  4. Maternal physiological changes in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Maternal_physiological...

    Total cortisol increases to three times of non-pregnant levels by the third trimester. [5] The increased estrogen in pregnancy leads to increase corticosteroid-binding globulin production and in response the adrenal gland produces more cortisol. [5] The net effect is an increase of free cortisol.

  5. A week-by-week guide to common pregnancy symptoms - AOL

    www.aol.com/news/week-week-guide-common...

    Here's a guide to pregnancy stages and symptoms of pregnancy week by week: First Trimester Pregnancy Symptoms. ... Welcome to the third and final trimester of pregnancy. Pregnancy Symptoms Week 28.

  6. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    TSH values may also be lower than normal (particularly in the first trimester) and the normal range should be adjusted for the stage of pregnancy. [ 8 ] [ 43 ] In pregnancy, subclinical hypothyroidism is defined as a TSH between 2.5 and 10 mIU/L with a normal thyroxine level, while those with TSH above 10 mIU/L are considered to be overtly ...

  7. Complications of pregnancy - Wikipedia

    en.wikipedia.org/wiki/Complications_of_pregnancy

    Placental abruption defined as the separation of the placenta from the uterus prior to delivery, is a major cause of third trimester vaginal bleeding and complicates about 1% of pregnancies. [13] [50] Symptomatic presentations are variable: Some women can entirely ignore the symptoms, while others have mild bleeding or abdominal discomfort and ...

  8. Human chorionic gonadotropin - Wikipedia

    en.wikipedia.org/wiki/Human_chorionic_gonadotropin

    Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.

  9. Thyroid-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Thyroid-stimulating_hormone

    A significant reduction in TSH suggests over-treatment. In both cases, a change in dose may be required. A low or low-normal TSH value may also signal pituitary disease in the absence of replacement. [citation needed] For hyperthyroid patients, both TSH and T 4 are usually monitored. In pregnancy, TSH measurements do not seem to be a good ...

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