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  2. XY sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XY_sex-determination_system

    Whilst XY sex determination is the most familiar, since it is the system that humans use, there are a range of alternative systems found in nature. The inverse of the XY system (called ZW to distinguish it) is used in birds and many insects, in which it is the females that are heterogametic (ZW), while males are homogametic (ZZ). [18]

  3. Sex linkage - Wikipedia

    en.wikipedia.org/wiki/Sex_linkage

    Females possessing one X-linked recessive mutation are considered carriers and will generally not manifest clinical symptoms of the disorder, although differences in X chromosome inactivation can lead to varying degrees of clinical expression in carrier females since some cells will express one X allele and some will express the other. All ...

  4. Sex-determination system - Wikipedia

    en.wikipedia.org/wiki/Sex-determination_system

    In some species, there are hermaphrodites, i.e., individuals that can function reproductively as either female or male. [2] There are also some species in which only one sex is present, temporarily or permanently. This can be due to parthenogenesis, the act of a female reproducing without fertilization.

  5. Sexual differentiation in humans - Wikipedia

    en.wikipedia.org/wiki/Sexual_differentiation_in...

    In the absence of a Y chromosome, the fetus will undergo female development. This is because of the presence of the sex-determining region of the Y chromosome, also known as the SRY gene. [5] Thus, male mammals typically have an X and a Y chromosome (XY), while female mammals typically have two X chromosomes (XX).

  6. Sex chromosome - Wikipedia

    en.wikipedia.org/wiki/Sex_chromosome

    The first 22 pairs are called autosomes. Autosomes are homologous chromosomes i.e. chromosomes which contain the same genes (regions of DNA) in the same order along their chromosomal arms. The 23rd pair of chromosomes are called allosomes. These consist of two X chromosomes in females, and an X chromosome and a Y chromosome in males. Females ...

  7. Fabry disease - Wikipedia

    en.wikipedia.org/wiki/Fabry_disease

    Fabry disease is sometimes diagnosed using a blood test that measures the activity of the affected enzyme called alpha-galactosidase, but genetic testing is also sometimes used, particularly in females. The treatment for Fabry disease varies depending on the organs affected by the condition, and the underlying cause can be addressed by ...

  8. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...

  9. Human genetics - Wikipedia

    en.wikipedia.org/wiki/Human_genetics

    Human genetics is the study of inheritance as it occurs in human beings.Human genetics encompasses a variety of overlapping fields including: classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population genetics, developmental genetics, clinical genetics, and genetic counseling.