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The remaining copy of the tumor suppressor gene can be inactivated by a point mutation or via other mechanisms, resulting in a loss of heterozygosity event, and leaving no tumor suppressor gene to protect the body. Loss of heterozygosity does not imply a homozygous state (which would require the presence of two identical alleles in the cell).
In medical genetics, compound heterozygosity is the condition of having two or more heterogeneous recessive alleles at a particular locus that can cause genetic disease in a heterozygous state; that is, an organism is a compound heterozygote when it has two recessive alleles for the same gene, but with those two alleles being different from each other (for example, both alleles might be ...
Heterozygosity values of 51 worldwide human populations. [10] Sub-Saharan Africans have the highest values in the world. In population genetics, the concept of heterozygosity is commonly extended to refer to the population as a whole, i.e., the fraction of individuals in a population that are heterozygous for a particular locus. It can also ...
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The Ho Chi Minh City University of Technology (HCMUT; Vietnamese: Trường Đại học Bách khoa, Đại học Quốc gia Thành phố Hồ Chí Minh, lit. 'Polytechnic of Vietnam National University, Ho Chi Minh City') [1] is a research university in Ho Chi Minh City, Vietnam. HCMUT is a member of Vietnam National University, Ho Chi Minh ...
HCMUSSH was formerly known as the College of Letters, University of Saigon (Vietnamese: Trường Đại học Văn khoa, Viện Đại học Sài Gòn). It is now the biggest research and training center in the field of social sciences and humanities in Southern Vietnam. In October 2021, HCMUSSH officially claimed their autonomy in the ...
In October 1945, President Hồ Chí Minh signed the decree to establish the University of Literature (Ban Đại học Văn khoa, or Trường Đại học Văn khoa) -the precursor of the current VNU-USSH. In April 1956, the University of Hanoi (Trường Đại học Tổng hợp Hà Nội) was established. During this period, fundamental ...
A significantly lower proportion of HLA-DRB1 heterozygosity exists among HCV-infected cases than uninfected cases. The differences were more pronounced with alleles represented as functional supertypes (P = 1.05 × 10 −6 ) than those represented as low-resolution genotypes (P = 1.99 × 10 −3 ).