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The treatment with steroids was stopped and three years later (while still taking buspirone, albuterol, fluticasone and salmeterol inhalers, loratadine and theophylline) the boy showed gradual improvement, but MRI brain scans revealed that the patient's hippocampal volume was 19.5% smaller than that of his twin.
Studies found that overusing anabolic-androgenic steroids can cause mood swings, impulsive, and aggressive behavior. [104] This behavior is associated with decreased emotion regulation systems such as the frontal cortex, temporal, parietal, and occipital. [105]
Mood swings. Weakened immune system. Weight gain. Prednisone can also cause some serious but rare side effects, including high blood pressure. And it’s possible to be allergic to prednisone ...
Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]
Therapeutic doses may cause a feeling of artificial well-being ("steroid euphoria"). [22] The neuropsychiatric effects are partly mediated by sensitization of the body to the actions of adrenaline. Therapeutically, the bulk of corticosteroid dose is given in the morning to mimic the body's diurnal rhythm; if given at night, the feeling of being ...
Moon face is among the most frequently reported adverse events of systemic glucocorticoids, along with insomnia (58%), mood disturbances (50%), and hyperphagia (49%). [ 8 ] Another long-term study of 88 patients on prednisone showed that lipodystrophy, such as moon face, was the most frequent adverse event, experienced by 63% of patients.
Any damage to the brain can cause a mental disorder. The brain is the control system for the nervous system and the rest of the body. Without it, the body cannot function properly. [71] Increased mood swings, insane behavior, and substance abuse disorders are traumatic brain injury (TBI) examples. Findings on the relationship between TBI ...
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