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Metoprolol is a beta blocker, or an antagonist of the β-adrenergic receptors. It is specifically a selective antagonist of the β 1-adrenergic receptor and has no intrinsic sympathomimetic activity. [37] Metoprolol exerts its effects by blocking the action of certain neurotransmitters, specifically adrenaline and noradrenaline.
Regarding non-cardiac side effects, they can cause nausea, headache, fatigue, dry mouth, and dry eyes. [4] In rare cases, confusion , memory loss , and sexual dysfunction are reported. [ 12 ] Additionally, beta 1 blockers can mask hypoglycaemia-induced tachycardia in diabetic patients, potentially leading to hypoglycaemic unawareness and ...
Beta blockers vary in their lipophilicity (fat solubility) and in turn in their ability to cross the blood–brain barrier and exert effects in the central nervous system. [76] Beta blockers with greater blood–brain barrier permeability can have both neuropsychiatric therapeutic benefits and side effects, as well as adverse cognitive effects ...
Additional hypotensive effects may occur when patients are taking beta-1 blockers with other antihypertensive drugs such as nitrates, PDE inhibitors, ACE inhibitors and calcium channel blockers. [17] The combination of beta blockers and antihypertensive drugs will work on different mechanism to lower blood pressure. [17]
A sympatholytic (sympathoplegic) drug is a medication that opposes the downstream effects of postganglionic nerve firing in effector organs innervated by the sympathetic nervous system (SNS). [1] They are indicated for various functions; for example, they may be used as antihypertensives .
Ben Tarver, 29, began having seizures and panic attacks in September before exhibiting symptoms of paranoia. By the middle of October, he was diagnosed with Anti-NMDA Receptor Encephalitis, a rare ...
Adrenergic competitive antagonists are shorter lasting than the other two types of antagonists. While the antagonists for alpha and beta receptors are usually different compounds, there has been recent drug development that effects both types of the adrenoreceptors. Phentolamine, an adrenergic antagonist
Lighter Side. Medicare. News. Science & Tech. Shopping. Sports. Weather. Overnight snow, freezing rain could make for icy roads Monday morning. NBC New York. Updated December 16, 2024 at 9:37 AM.
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