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Pulmonary fibrosis is a condition in which the lungs become scarred over time. [1] Symptoms include shortness of breath , a dry cough, feeling tired, weight loss, and nail clubbing . [ 1 ] Complications may include pulmonary hypertension , respiratory failure , pneumothorax , and lung cancer .
503 Pneumoconiosis due to other inorganic dust; 504 Pneumonopathy due to inhalation of other dust; 505 Pneumoconiosis, unspecified; 506 Respiratory conditions due to chemical fumes and vapors; 507 Pneumonitis due to solids and liquids; 508 Respiratory conditions due to other and unspecified external agents 508.0 Acute pulmonary manifestations ...
Idiopathic pulmonary fibrosis (IPF) synonymous with cryptogenic fibrosing alveolitis [5] is a rare, progressive illness of the respiratory system, characterized by the thickening and stiffening of lung tissue, associated with the formation of scar tissue.
The median survival in idiopathic pulmonary fibrosis is 3-3.5 years. In those who receive a lung transplant, the medial survival in idiopathic pulmonary fibrosis is 5.2 years, as compared to 6.7 years in those with other types of ILD. [8] ILD is associated with a 3-fold increased risk of lung cancer. [8]
Infant respiratory distress syndrome due to a deficiency of surfactant in the lungs of a baby born prematurely. Tuberculosis [4] Many cases of restrictive lung disease are idiopathic (have no known cause). Still, there is generally pulmonary fibrosis. [5] Examples are: Idiopathic pulmonary fibrosis
Although fibrosis is not a normal feature of these subtypes, repair strategies in end-stage emphysema may lead to pulmonary fibrosis. [14] The fourth subtype is known as paracicatricial emphysema or irregular emphysema, involves the acinus irregularly and is associated with fibrosis.
While a lung biopsy is the gold standard, some clinicians opt against this due to the risks of the procedure. Lung biopsies performed on patients with NSIP reveal two different disease patterns – cellular and fibrosing – which are associated with different prognoses. The cellular pattern displays chronic inflammation with minimal fibrosis.
Usual interstitial pneumonia (UIP) is a form of lung disease characterized by progressive scarring of both lungs. [1] The scarring (pulmonary fibrosis) involves the pulmonary interstitium (the supporting framework of the lung). UIP is thus classified as a form of interstitial lung disease.