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  2. One gene–one enzyme hypothesis - Wikipedia

    en.wikipedia.org/wiki/One_gene–one_enzyme...

    Proteins, Enzymes, Genes: The Interplay of Chemistry and Biology. New Haven: Yale University Press. ISBN 0-300-07608-8. Kay LE (1993). The Molecular Vision of Life: Caltech, The Rockefeller Foundation, and the Rise of the New Biology. New York: Oxford University Press. ISBN 0-19-511143-5. Morange M (1998). A History of Molecular Biology. Cobb M ...

  3. Molecular biology - Wikipedia

    en.wikipedia.org/wiki/Molecular_biology

    A major milestone in molecular biology was the discovery of the structure of DNA. This work began in 1869 by Friedrich Miescher, a Swiss biochemist who first proposed a structure called nuclein, which we now know to be (deoxyribonucleic acid), or DNA. [15]

  4. IUBMB Life - Wikipedia

    en.wikipedia.org/wiki/IUBMB_Life

    It is one of four official journals of the IUBMB. The journal is published monthly by John Wiley & Sons. According to the Journal Citation Reports, the journal has a 2020 impact factor of 3.885, ranking it 147th out of 297 journals in the category "Biochemistry and Molecular Biology" [1] and 121st out of 195 journals in the category "Cell ...

  5. Microbial genetics - Wikipedia

    en.wikipedia.org/wiki/Microbial_Genetics

    The results of these experiments led directly to the one gene-one enzyme hypothesis that specific genes code for specific proteins. This concept proved to be the opening gun in what became molecular genetics and all the developments that have followed from that. [30] Saccharomyces cerevisiae is a yeast of the phylum Ascomycota.

  6. List of unsolved problems in biology - Wikipedia

    en.wikipedia.org/wiki/List_of_unsolved_problems...

    What was the molecular mechanism that allows the association of the amino acids with their triplet codons? [1] What were the biochemical paths from individual bio-building blocks like amino acids or nucleic acids to functional polymers such as proteins and DNA?

  7. Griffith's experiment - Wikipedia

    en.wikipedia.org/wiki/Griffith's_experiment

    Griffith's experiment discovering the "transforming principle" in Streptococcus pneumoniae (pneumococcal) bacteria.. Griffith's experiment, [1] performed by Frederick Griffith and reported in 1928, [2] was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation.

  8. Central dogma of molecular biology - Wikipedia

    en.wikipedia.org/wiki/Central_dogma_of_molecular...

    [12] [13] However, Rosalind Ridley in Molecular Pathology of the Prions (2001) has written that "The prion hypothesis is not heretical to the central dogma of molecular biology—that the information necessary to manufacture proteins is encoded in the nucleotide sequence of nucleic acid—because it does not claim that proteins replicate ...

  9. Hershey–Chase experiment - Wikipedia

    en.wikipedia.org/wiki/Hershey–Chase_experiment

    Hershey and Chase, along with others who had done related experiments, confirmed that DNA was the biomolecule that carried genetic information. Before that, Oswald Avery, Colin MacLeod, and Maclyn McCarty had shown that DNA led to the transformation of one strain of Streptococcus pneumoniae to another. The results of these experiments provided ...