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Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic. [6] It is available as a generic medication. [9] [10] [11]
The Calpol brand name is likely a combination of 'Calmic' and 'paracetamol'. [6] Calmic was acquired by Wellcome (today GlaxoSmithKline) in 1966, and Calpol became one of Wellcome's best-selling UK products in the 1980s. [6] The brand was later owned by Pfizer Consumer Healthcare, which was acquired by Johnson & Johnson in 2006. [7]
Ibuprofen, an analgesic and non-steroidal anti-inflammatory drug (NSAID), [1] is sold under many brand-names around the world. The most common are Brufen (its earliest registered trademark), Advil, Motrin, and Nurofen .
The combinations of paracetamol and NSAIDs ibuprofen or diclofenac are promising, possibly offering better pain control than either paracetamol or the NSAID alone. [ 25 ] [ 26 ] [ 68 ] [ 69 ] Additionally, the paracetamol/ibuprofen combination may be superior to paracetamol/codeine and ibuprofen/codeine combinations.
ATC code M01 Anti-inflammatory and antirheumatic products is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
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Capsaicin/diclofenac – combination of a TRPV1 agonist and a COX-2 inhibitor for topical application [25] CMX-020 – TRPV1 modulator as well as CB 1 and CB 2 receptor modulator [26] DWP-05195 (TR-1) – TRPV1 antagonist [27] GRC-6211 – TRPV1 agonist [28] JNJ-38893777 – TRPV1 antagonist [29] Mavatrep (JNJ‐39439335) – TRPV1 antagonist.
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