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The concept of grading of the tumors of the central nervous system, agreeing for such the regulation of the "progressiveness" of these neoplasias (from benign and localized tumors to malignant and infiltrating tumors), dates back to 1926 and was introduced by P. Bailey and H. Cushing, [1] in the elaboration of what turned out the first systematic classification of gliomas.
Trachoma is an infectious disease caused by bacterium Chlamydia trachomatis. [2] The infection causes a roughening of the inner surface of the eyelids. [2] This roughening can lead to pain in the eyes, breakdown of the outer surface or cornea of the eyes, and eventual blindness. [2]
C. trachomatis is the single most important infectious agent associated with blindness (trachoma), and it also affects the eyes in the form of inclusion conjunctivitis and is responsible for about 19% of adult cases of conjunctivitis. [6] C. trachomatis in the lungs presents as the chlamydia pneumoniae respiratory infection and can affect all ...
Trachoma Gold Medal awarded by the French Ligue Internationale Contre le Trachome (1996). Ophthalmological Society of South Africa (2005). Mamphela Ramphele , a South African politician and an activist against apartheid , praised Erika as a “fellow global citizen, [who] not only opened the physical eyes of those she encountered but also their ...
Grading in cancer is distinguished from staging, which is a measure of the extent to which the cancer has spread. Pathology grading systems classify the microscopic cell appearance abnormality and deviations in their rate of growth with the goal of predicting developments at tissue level (see also the 4 major histological changes in dysplasia ).
1.3.3 Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype 1.3.4 Infant-type hemispheric glioma 1.4 Circumscribed astrocytic gliomas 1.4.1 Pilocytic astrocytoma 1.4.2 High-grade astrocytoma with piloid features 1.4.3 Pleomorphic xanthoastrocytoma 1.4.4 Subependymal giant cell astrocytoma 1.4.5 Chordoid glioma
G (1–4): the grade of the cancer cells (i.e. they are "low grade" if they appear similar to normal cells, and "high grade" if they appear poorly differentiated) S (0–3): elevation of serum tumor markers; R (0–2): the completeness of the operation (resection-boundaries free of cancer cells or not) Pn (0–1): invasion into adjunct nerves
Chronic conjunctivitis (e.g. trachoma) and aging factor are two causes of conjunctival concretion, which will make the conjunctiva cellular degeneration to produce an epithelial inclusion cyst, filled with epithelial cells and keratin debris. After calcification, the conjunctival cyst hardens and forms a conjunctival concretion. Congenital ...