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  2. Heterophile antibody - Wikipedia

    en.wikipedia.org/wiki/Heterophile_antibody

    Heterophile antibodies can arise in non-EBV infections. False positive monospot tests may occur in cases of HIV, lymphoma, or systemic lupus erythematosus. Other assays for detection of EBV are available, including serologic markers. [7] An important clinical pearl for heterophile antibodies is they can also be seen in genetic immunodeficiencies.

  3. Heterophile antibody test - Wikipedia

    en.wikipedia.org/wiki/Heterophile_antibody_test

    Rarely, however, a false positive heterophile antibody test may result from systemic lupus erythematosus, toxoplasmosis, rubella, lymphoma and leukemia. [7] However, the sensitivity is only moderate, so a negative test does not exclude EBV. This lack of sensitivity is especially the case in young children, many of whom will not produce ...

  4. Diagnosis of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Diagnosis_of_HIV/AIDS

    The specificity rate given here for the inexpensive enzyme immunoassay screening tests indicates that, in 1,000 HIV test results of healthy individuals, about 15 of these results will be a false positive. Confirming the test result (i.e., by repeating the test, if this option is available) could reduce the ultimate likelihood of a false ...

  5. Cross-reactivity - Wikipedia

    en.wikipedia.org/wiki/Cross-reactivity

    An example of helpful cross-reactivity is in heterophile antibody tests, which detect Epstein-Barr virus using antibodies with specificity for other antigens. Cross-reactivity is also a commonly evaluated parameter for the validation of immune and protein binding based assays such as ELISA and RIA .

  6. False positives and false negatives - Wikipedia

    en.wikipedia.org/wiki/False_positives_and_false...

    The false positive rate (FPR) is the proportion of all negatives that still yield positive test outcomes, i.e., the conditional probability of a positive test result given an event that was not present. The false positive rate is equal to the significance level. The specificity of the test is equal to 1 minus the false positive rate.

  7. What Really Causes a False Positive COVID-19 Test? Experts ...

    www.aol.com/false-positive-covid-19-test...

    False positive COVID-19 tests—when your result is positive, but you aren’t actually infected with the SARS-CoV-2 virus—are a real, if unlikely, possibility, especially if you don’t perform ...

  8. Hook effect - Wikipedia

    en.wikipedia.org/wiki/Hook_effect

    Since the antibodies do not bridge between antigens, no agglutination occurs. Because no agglutination occurs, the test is interpreted as negative. In this case, the result is a false negative. The range of relatively high antibody concentrations within which no reaction occurs is called the prozone. [5]

  9. Are False Positive Covid Tests Common? Doctors Explain. - AOL

    www.aol.com/false-positive-covid-tests-common...

    A false positive Covid-19 test result can happen, but it’s rare, says Brian Labus, Ph.D., M.P.H., assistant professor at the University of Nevada Las Vegas School of Public Health.