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Histopathology of aspergilloma, H&E staining. The most common organ affected by aspergilloma is the lung. Aspergilloma mainly affects people with underlying cavitary lung disease such as tuberculosis, sarcoidosis, bronchiectasis, cystic fibrosis and systemic immunodeficiency.
Some forms are intertwined; for example ABPA and simple aspergilloma can progress to CPA. Other, noninvasive manifestations include fungal sinusitis (both allergic in nature and with established fungal balls), otomycosis (ear infection), keratitis (eye infection), and onychomycosis (nail infection).
An aspergilloma is a fungus ball composed of Aspergillus hypha - the long filamentous strands which extend from the fungus to enable growth and reproduction. [13] They can arise within any bodily cavity, though in chronic pulmonary aspergillosis they form within pulmonary cavities that have been colonized by Aspergillus spp.
Aspergilloma, a "fungus ball" that can form within cavities such as the lung; Disseminated invasive aspergillosis, an infection spread widely through the body; Fungal infections from Aspergillus spores remain one theory of sickness and untimely death of some early Egyptologists and tomb explorers.
Allergic bronchopulmonary aspergillosis; Other names: ABPA, Hinson-Pepys disease. The chest radiograph of an allergic bronchopulmonary aspergillosis patient shown with left-sided perihilar opacity (blue arrow) along with non-homogeneous infiltrates (transient pulmonary infiltrates indicated by red arrows) in all zones of both lung fields.
Fungal infection, also known as mycosis, is a disease caused by fungi. [5] [13] Different types are traditionally divided according to the part of the body affected; superficial, subcutaneous, and systemic.
Aspergilloma In radiology , the air crescent sign is a finding on chest radiograph and computed tomography that is crescenteric and radiolucent , due to a lung cavity that is filled with air and has a round radiopaque mass. [ 1 ]
Aspergilloma in an old tuberculosis cavity; healed, calcified tuberculous lesions are also present towards the right of the image Healed tuberculous cavity, where the entire left lung is destroyed. Post-tuberculosis lung disease (PTLD) is ongoing lung disease that is caused by tuberculosis (TB) but persists after the infection is cured. [1]