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Without cyclin, CDK is less active than in the cyclin-CDK heterodimer complex. [ 5 ] [ 6 ] CDKs phosphorylate proteins on serine (S) or threonine (T) residues. The specificity of CDKs for their substrates is defined by the S/T-P-X-K/R sequence, where S/T is the phosphorylation site, P is proline, X is any amino acid, and the sequence ends with ...
Dynamo is a set of techniques that together can form a highly available key-value structured storage system [1] or a distributed data store. [1] It has properties of both databases and distributed hash tables (DHTs).
In CDK-cyclin complexes, this activation region is composed of a conserved αL-12 Helix and contains a key phosphorylatable residue (usually Threonine for CDK-cyclin partners, but also includes Serine and Tyrosine) that mediates the enzymatic activity of the CDK. It is at this essential residue (T160 in CDK2 complexes, T177 in CDK6 complexes ...
Just like indexing systems in the relational model, DynamoDB demands that any updates to a table be reflected in each of the table's indices. DynamoDB handles this using a service it calls the "log propagator", which subscribes to the replication logs in each node and sends additional Put, Update, and Delete requests to indices as necessary. [ 30 ]
Few things will put a damper on your vacation or holiday faster than food poisoning.The intense stomach pain, rushing to the toilet and feeling relegated to bed keeps just about everyone out of ...
Download as PDF; Printable version; In other projects Appearance. move to sidebar hide. From Wikipedia, the free encyclopedia. Redirect page. Redirect to: Amazon ...
Martin described Mangione as someone who led a book club for some of the Surfbreak residents and enjoyed doing active activities such as hiking and yoga. But he also remembered when Mangione first ...
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