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  2. Intrauterine transfusion - Wikipedia

    en.wikipedia.org/wiki/Intrauterine_transfusion

    An Intrauterine transfusion (IUT) is a procedure that provides blood to a fetus, most commonly through the umbilical cord. [1] [2] It is used in cases of severe fetal anemia, such as when fetal red blood cells are being destroyed by maternal antibodies, or parvovirus B19 infection, homozygous alpha-thalassemia, or twin-to-twin transfusion syndrome. [3]

  3. Fetal circulation - Wikipedia

    en.wikipedia.org/wiki/Fetal_circulation

    The fetal circulation is composed of the placenta, umbilical blood vessels encapsulated by the umbilical cord, heart and systemic blood vessels. A major difference between the fetal circulation and postnatal circulation is that the lungs are not used during the fetal stage resulting in the presence of shunts to move oxygenated blood and ...

  4. Percutaneous umbilical cord blood sampling - Wikipedia

    en.wikipedia.org/wiki/Percutaneous_umbilical...

    Percutaneous umbilical cord blood sampling (PUBS), also called cordocentesis, fetal blood sampling, or umbilical vein sampling is a diagnostic genetic test that examines blood from the fetal umbilical cord to detect fetal abnormalities. [1] Fetal and maternal blood supply are typically connected in utero with one

  5. Fetal-maternal haemorrhage - Wikipedia

    en.wikipedia.org/wiki/Fetal-maternal_haemorrhage

    It is estimated that less than 1ml of fetal blood is lost to the maternal circulation during normal labour in around 96% of normal deliveries. [1] [2] The loss of this small amount of blood may however be a sensitising event and stimulate antibody production to the foetal red blood cells, an example of which is Rhesus disease of the newborn.

  6. Maternal–fetal medicine - Wikipedia

    en.wikipedia.org/wiki/Maternal–fetal_medicine

    The development of amniocentesis in 1952, fetal blood sampling during labor in the early 1960s, more precise fetal heart monitoring in 1968, and real-time ultrasound in 1971 resulted in early intervention and lower mortality rates. [2]

  7. Hemolytic disease of the newborn (ABO) - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_disease_of_the...

    IgG anti-A (or IgG anti-B) antibodies that enter the fetal circulation from the mother find A (or B) antigens on many different fetal cell types, leaving fewer antibodies available for binding onto fetal red blood cells. [14] Fetal RBC surface A and B antigens are not fully developed during gestation and so there are a smaller number of ...

  8. Cell-free fetal DNA - Wikipedia

    en.wikipedia.org/wiki/Cell-free_fetal_DNA

    Cell-free fetal DNA sheds into the maternal blood circulation. cffDNA originates from placental trophoblasts. [1] [2] Fetal DNA is fragmented when placental microparticles are shed into the maternal blood circulation. [3] cffDNA fragments are approximately 200 base pairs (bp) in length. They are significantly smaller than maternal DNA fragments ...

  9. Neonatal alloimmune thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Neonatal_alloimmune...

    Additionally, platelet antigen genotyping can be performed on the maternal and paternal blood to determine the exact nature of the incompatibility. [citation needed] Neonatal platelet counts on laboratory testing are typically under 20,000 μL −1. Higher counts may suggest a different diagnosis, such as maternal immune thrombocytopenic ...

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