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Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [1] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2]
Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [10] For pain or fever, effects typically begin within 30 minutes. [10] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [10] One common adverse effect is an upset ...
You might only experience high blood pressure symptoms if your blood pressure is very high. Very high blood pressure can cause symptoms like: Nosebleeds. Anxiety. Severe headaches. Chest pain ...
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). [1] Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction.
High blood pressure—Comprehensive overview covers symptoms, treatment, ... High blood pressure—Comprehensive overview covers symptoms, treatment, and prevention of hypertension.
With high blood pressure, the force of blood flowing through your blood vessels is consistently too high. Around 75 million Americans have high blood pressure (or hypertension), and almost half of ...
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