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In hematology, erythrocyte deformability refers to the ability of erythrocytes (red blood cells, RBCs) to change shape under a given level of applied stress without hemolysing (rupturing). This is an important property because erythrocytes must change their shape extensively under the influence of mechanical forces in fluid flow or while ...
It also occurs in diabetes mellitus and is one of the causative factors for microvascular occlusion in diabetic retinopathy. So, the presence of rouleaux can also be a cause of disease because it will restrict the flow of blood throughout the body because capillaries can only accept free-flowing singular and independent red blood cells.
A biconcave disc. In geometry and mathematical biology, a biconcave disc — also referred to as a discocyte [1] — is a geometric shape resembling an oblate spheroid with two concavities on the top and on the bottom. Biconcave discs appear in the study of cell biology, as an approximation to the shape of certain cells, including red blood cells.
For instance, anemia (low red blood cell concentration) reduces viscosity, whereas increased red blood cell concentration increases viscosity. It had been thought that aspirin and related " blood thinner " drugs decreased the viscosity of blood, but instead studies found that they act by reducing the tendency of the blood to clot.
Red blood cells (RBCs), referred to as erythrocytes (from Ancient Greek erythros 'red' and kytos 'hollow vessel', with -cyte translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, [1] erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O 2) to the body tissues—via ...
Two clusters of faces of the bilunabirotunda, the lunes (each lune featuring two triangles adjacent to opposite sides of one square), can be aligned with a congruent patch of faces on the rhombicosidodecahedron. If two bilunabirotundae are aligned this way on opposite sides of the rhombicosidodecahedron, then a cube can be put between the ...
Note the increased central pallor of the red blood cells. Hypochromic anemia is a generic term for any type of anemia in which the red blood cells are paler than normal. (Hypo- refers to less, and chromic means colour.) A normal red blood cell has a biconcave disk shape and will have an area of pallor in its center when viewed microscopically.
Hereditary elliptocytosis, also known as ovalocytosis, is an inherited blood disorder in which an abnormally large number of the person's red blood cells are elliptical rather than the typical biconcave disc shape. Such morphologically distinctive erythrocytes are sometimes referred to as elliptocytes or ovalocytes.