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Carbimazole (brand names Neo-Mercazole, Anti-Thyrox, etc.) is used to treat hyperthyroidism. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole . Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin , hence reducing the production of the ...
Thyroid diseases are highly prevalent worldwide, [10] [11] [12] and treatment varies based on the disorder. Levothyroxine is the mainstay of treatment for people with hypothyroidism, [13] while people with hyperthyroidism caused by Graves' disease can be managed with iodine therapy, antithyroid medication, or surgical removal of the thyroid ...
[68] [69] Dogs which display coprophagy, the consumption of feces, and also live in a household with a dog receiving levothyroxine treatment, may develop hyperthyroidism if they frequently eat the feces from the dog receiving levothyroxine treatment. [70] Hyperthyroidism may occur if a dog eats an excessive amount of thyroid gland tissue.
The Wolff–Chaikoff effect has been used as a treatment principle against hyperthyroidism (especially thyroid storm) by infusion of a large amount of iodine to suppress the thyroid gland. Iodide was used to treat hyperthyroidism before antithyroid drugs such as propylthiouracil and methimazole were developed.
It occurs about 7.5 times more often in women than in men. [1] Often, it starts between the ages of 40 and 60, but can begin at any age. [6] It is the most common cause of hyperthyroidism in the United States (about 50 to 80% of cases). [1] [4] The condition is named after Irish surgeon Robert Graves, who described it in 1835. [6]
Nearly five out of 100 Americans age 12 and older have hypothyroidism, and it is most commonly diagnosed in women and those over age 60, per the National Institute of Diabetes and Digestive and ...
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