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Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [10] cSCC typically presents as a hard lump with a scaly surface, though it may also present as an ulcer. [1]
Skin cancer is the most commonly diagnosed form of cancer in humans. [11] [12] [13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. [1] The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC).
With doctors who are experts in dermatoscopy, the diagnostic accuracy for melanoma is significantly better than those who do not have any specialized training. [3] Thus, there is considerable improvement in the sensitivity (detection of melanomas) as well as specificity (percentage of non-melanomas correctly diagnosed as benign), compared with naked eye examination.
With advances in medical treatments in recent decades, non-melanoma skin cancer has an extremely high survival rate, especially in the U.S. Basal cell carcinoma and squamous cell carcinoma are the ...
However, magnetic resonance imaging (MRI) scans are not associated with a radiation risk, and MRI scans are being evaluated for their use in cancer screening. [51] There is a significant risk of detecting incidentalomas - benign lesions that might be misinterpreted as cancer and put patients at potential risk by undergoing unnecessary follow-up ...
It is a rare type of skin cancer, with a 2013 incidence of only 0.7 per 100,000 persons in the U.S. [56] As of 2005, roughly 2,500 new cases of MCC are diagnosed each year in the United States, [56] as compared to around 60,000 new cases of malignant melanoma and over 1 million new cases of nonmelanoma skin cancer. [57]
Clear evidence establishes ultraviolet radiation, especially the non-ionizing medium wave UVB, as the cause of most non-melanoma skin cancers, which are the most common forms of cancer in the world. [40] Skin cancer may occur following ionizing radiation exposure following a latent period averaging 20 to 40 years.
Skin Cancer: Recognition and Management is a clinical reference by Robert A. Schwartz covering skin and accessible mucosal disorders, premalignant and malignant cutaneous disorders, including melanoma, Kaposi's sarcoma and other sarcomas, cutaneous lymphoma, cutaneous metastatic disease and cutaneous markers of internal malignancy.
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