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Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer , while one in the first part of the intestines is a duodenal ulcer . [ 1 ]
The alkaline environment causes the retained gastric tissue to produce acid, which may result in ulcers in a rare complication known as retained antrum syndrome. All patients lose weight after gastrectomy, although the extent of weight loss is dependent on the extent of surgery (total gastrectomy vs partial gastrectomy) and the pre-operative BMI.
Stomach cancers usually occur due to fluctuations in acidity level and may present with vague symptoms of abdominal fullness, weight loss and pain. The actual cause of stomach cancer is not known but has been linked to infection with Helicobacter pylori , pernicious anemia , Menetriere's disease, and nitrogenous preservatives in food.
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Most patients do remain obese (BMI 25-35) following surgery despite significant weight loss, and patients with BMI over 40 tended to lose more weight than those with BMI under 40. [ 29 ] [ 30 ] Concerning metabolic syndrome , bariatric surgery patients were able to achieve remission 2.4 times as often as those who underwent nonsurgical treatment.
Gastric erosion occurs when the mucous membrane lining the stomach becomes inflamed. Specifically, the term "erosion" in this context means damage that is limited to the mucosa, which consists of three distinct layers: the epithelium (in the case of a healthy stomach, this is non-ciliated simple columnar epithelium), the basement membrane, and the lamina propria.
Other possible symptoms include nausea and vomiting, bloating, loss of appetite and heartburn. [1] [2] Complications may include stomach bleeding, stomach ulcers, and stomach tumors. [1] When due to autoimmune problems, low red blood cells due to not enough vitamin B12 may occur, a condition known as pernicious anemia. [3]