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Bile acid synthesis occurs in liver cells, which synthesize primary bile acids (cholic acid and chenodeoxycholic acid in humans) via cytochrome P450-mediated oxidation of cholesterol in a multi-step process. Approximately 600 mg of bile salts are synthesized daily to replace bile acids lost in the feces, although, as described below, much ...
Heart-healthy soluble fiber is found in foods like oats, beans, lentils, edamame, fruits and vegetables. And it does more than just lower cholesterol. Soluble fiber has also been shown to promote ...
Chyme has a low pH that is countered by the production of bile, which helps the further digestion of food. Chyme is part liquid and part solid: a thick semifluid mass of partially digested food and digestive secretions that is formed in the stomach and small intestine during digestion. Chyme also contains cells from the mouth and esophagus that ...
Bile (yellow material) in a liver biopsy stained with hematoxylin-eosin in a condition called cholestasis (setting of bile stasi). Bile (from Latin bilis), or gall, is a yellow-green/misty green fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine.
Supplementation with vitamin C, vitamin D, and NAC can increase glutathione levels. [citation needed] Betaine hydrochloride is a lipotropic and increases gastric acid. [2] Betaine itself (in a non-hydrochloric form, also known as TMG or Trimethylglycine) also has a lipotropic effect. [3] Quinoa is high in betaine. [citation needed]
Secondary bile acids increase intracellular production of reactive oxygen and reactive nitrogen species resulting in increased oxidative stress and DNA damage. [30] [31] As shown in the figure below, deoxycholate added to the diet of mice increased the level of 8-oxo-dG, an oxidative DNA damage, in the colonic epithelium of mice. When the level ...
Bile acts partly as a surfactant which lowers the surface tension between either two liquids or a solid and a liquid and helps to emulsify the fats in the chyme. Food fat is dispersed by the action of bile into smaller units called micelles. The breaking down into micelles creates a much larger surface area for the pancreatic enzyme, lipase to ...
These water-soluble form, bile acids e.g., deoxycholic and lithocholic are adsorbed to dietary fiber and an increased fecal loss of sterols, dependent in part on the amount and type of fiber. A further factor is an increase in the bacterial mass and activity of the ileum as some fibers e.g., pectin are digested by bacteria.