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Antibiotics by mouth and by intravenous appear similar. [32] [33] Due to insufficient evidence it is unclear what the best antibiotic treatment is for osteomyelitis in people with sickle cell disease as of 2019. [34] Initial first-line antibiotic choice is determined by the patient's history and regional differences in common infective organisms.
The veterinary uses of clindamycin are quite similar to its human indications, and include treatment of osteomyelitis, [74] skin infections, and toxoplasmosis, for which it is the preferred drug in dogs and cats. [75] They can be used both by mouth and topically. [62] A disadvantage is that bacterial resistance can develop fairly quickly. [62]
Vertebral osteomyelitis often attacks two vertebrae and the corresponding intervertebral disk, causing narrowing of the disc space between the vertebrae. [6] The prognosis for the disease is dependent on where the infection is concentrated in the spine, the time between initial onset and treatment, and what approach is used to treat the disease.
Osteomyelitis of the jaws is osteomyelitis (which is infection and inflammation of the bone marrow, sometimes abbreviated to OM) which occurs in the bones of the jaws (i.e. maxilla or the mandible). Historically, osteomyelitis of the jaws was a common complication of odontogenic infection (infections of the teeth). Before the antibiotic era, it ...
The culture may be negative, even if there is an active infection. Treatment may still be considered even if the test results are negative, especially if the patient's history supports past fish or fish-tank exposure. [3] In the absence of positive culture results, a skin or tissue biopsy may be a helpful test to render a microscopic diagnosis. [3]
Surgery is the main treatment, often combined with antibiotics. The prognosis is generally favorable, with minimal risk of lasting disability or recurrence. Brodie abscess is responsible for 2.5%-42% of primary bone infections. It is named after Sir Benjamin Collins Brodie, 1st Baronet, who initially described the condition in the 1830s.
The infection can occur in the respiratory or urinary tracts, as it is a part of the normal flora in those two areas, and will develop into sepsis or septic arthritis. [7] Most K. kingae are sensitive to beta-lactam antibiotics, but reports describe strains producing beta-lactamases. [8] Options include aminoglycosides, macrolides and ...
In 2008, tentative evidence showed rifampicin may be useful in the treatment of methicillin-resistant Staphylococcus aureus in combination with other antibiotics, including in difficult-to-treat infections such as osteomyelitis and prosthetic joint infections. [20]
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