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A microscopy slide scanner. Whole slide image quality comparison, with a slide scanned with a 20x objective and about 0.8 gigabytes (GB) in size to the left, and a 40x objective and approximately 1.2 GB in size to the right. Each image shows a red blood cell. Digital slides are created from glass slides using specialized scanning machines.
Alexander Murray and Richard Morse invented and patented the first analog color scanner at Eastman Kodak in 1937. Intended for color separation at printing presses, their machine was an analog drum scanner that imaged a color transparency mounted in the drum, with a light source placed underneath the film, and three photocells with red, green, and blue color filters reading each spot on the ...
Prior to recent advances in virtual microscopy, slides were commonly digitized by various forms of film scanner and image resolutions rarely exceeded 5000 dpi. Nowadays, it is possible to achieve more than 100,000 dpi and thus resolutions approaching that visible under the optical microscope .
Digital slides can be retrieved from a storage system, and viewed on a computer screen, by running image management software on a standard web browser, and assessed in exactly the same way as on a microscope. [1] Digital slides can be used as an alternative to traditional viewing for the purpose of teleconsultation. [2]
A stereopticon is a slide projector or relatively powerful "magic lantern", which has two lenses, usually one above the other, and has mainly been used to project photographic images. These devices date back to the mid 19th century, [ 1 ] and were a popular form of entertainment and education before the advent of moving pictures .
Expense is an issue with real-time systems and virtual slide systems as they can be costly. Virtual slide telepathology is emerging as the technology of choice for telepathology services. However, high throughput virtual slide scanners (those producing one virtual slide or more per minute) are currently expensive.
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