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The rate of nausea was lower among male (8%) and elderly (19%) patients. No patients in the clinical studies were hospitalized due to nausea.) Diarrhea: ~12% (2% were severe, and 2% of patients discontinued treatment due to diarrhea) Several less common adverse reactions (<1%). For opioid-induced constipation:
Constipation is the most common chronic gastrointestinal disorder in adults. Depending on the definition employed, it occurs in 2% to 20% of the population. [18] [58] It is more common in women, the elderly and children. [58] Specifically constipation with no known cause affects females more often affected than males. [59]
Most of us will experience some degree of constipation at some point in our lives, and studies show that at least 15% of the population will experience chronic constipation.
Metabolic alkalosis is the most common acid-base imbalance observed. [26] Other significant adverse effects include rhabdomyolysis , [ 26 ] steatorrhoea , [ 26 ] inflammation and ulceration of colonic mucosa, [ 26 ] pancreatitis , [ 26 ] [ 27 ] kidney failure , [ 26 ] [ 28 ] [ 29 ] factitious diarrhea [ 26 ] [ 30 ] and other problems. [ 26 ]
7. Move more. You may notice that if you take a break from your exercise routine, you get more backed up. “A more sedentary state leads to more constipation,” says Dr. Mathur, who adds that ...
Constipation is no fun. Yet, it’s incredibly common. According to the National Institute of Diabetes and Digestive and Kidney Diseases, roughly 16% of U.S. adults struggle with it. And if you ...
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