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Aripiprazole was frequently found to be a partial agonist or full agonist, with an intrinsic activity that could be low (5-HT 2A, 5-HT 7), intermediate (D 2L, 5-HT1A), or high (5-HT 2C). This mixture of agonist actions at D2-dopamine receptors is consistent with the hypothesis that aripiprazole has "functionally selective" actions. [92]
Aripiprazole (Abilify) – dopamine D 2 and D 3 partial agonist, serotonin 5-HT 1A and 5-HT 7 receptor partial agonist, serotonin 5-HT 2A and 5-HT 2B receptor antagonist or inverse agonist, and atypical antipsychotic [96] [97]
Antipsychotics by class Generic name Brand names Chemical class ATC code Typical antipsychotics; Acepromazine: Atravet, Acezine: phenothiazine: N05AA04
Third-generation antipsychotics were introduced in the 2000s and offer partial agonism, rather than blockade, of dopamine receptors. [14] Neuroleptic , originating from Ancient Greek : νεῦρον ( neuron ) and λαμβάνω ( take hold of )—thus meaning "which takes the nerve" —refers to both common neurological effects and side effects.
AR-08 – adrenergic receptor agonist [65] Aripiprazole (Abilify, Abilify Maintena, Abilify MyCite, Abilitat, Ao Pai, Aripiprazole depot, Aripiprazole ECER tablets, Arlemide; OPC-14597, OPC-14597 IMD, OPC-31) – atypical antipsychotic / dopamine receptor partial agonist and serotonin receptor modulator [66]
A dopamine agonist is a ... (Partial agonist of the D 2 family receptors - Trade name "Abilify" in the United States; atypical antipsychotic) Brexpiprazole (Partial ...
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
Stelazine (trifluoperazine) – an antipsychotic used in the treatment of psychotic disorders, anxiety, and nausea caused by chemotherapy [2] Strattera (atomoxetine) – a non-stimulant medication used to treat ADHD; Suboxone (buprenorphine/naloxone) - a partial opioid agonist used in the treatment of opioid use disorder
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