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  2. IRF1 - Wikipedia

    en.wikipedia.org/wiki/IRF1

    3659 16362 Ensembl ENSG00000125347 ENSMUSG00000018899 UniProt P10914 P15314 RefSeq (mRNA) NM_002198 NM_001159393 NM_001159396 NM_008390 RefSeq (protein) NP_002189 NP_001341853 NP_001341854 NP_001152865 NP_001152868 NP_032416 Location (UCSC) n/a Chr 11: 53.66 – 53.67 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interferon regulatory factor 1 is a protein that in humans is encoded ...

  3. Interferon regulatory factors - Wikipedia

    en.wikipedia.org/wiki/Interferon_regulatory_factors

    Interferon regulatory factors (IRF) are proteins which regulate transcription of interferons (see regulation of gene expression). [1] Interferon regulatory factors contain a conserved N-terminal region of about 120 amino acids, which folds into a structure that binds specifically to the IRF-element (IRF-E) motifs, which is located upstream of the interferon genes. [2]

  4. IRF3 - Wikipedia

    en.wikipedia.org/wiki/IRF3

    IRF3 is a member of the interferon regulatory transcription factor (IRF) family. [5] IRF3 was originally discovered as a homolog of IRF1 and IRF2.IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. [6]

  5. Immediate Response Force - Wikipedia

    en.wikipedia.org/wiki/Immediate_Response_Force

    By 1980, the United States formed the Rapid Deployment Joint Task Force (RDJTF) as a rapid reaction force under the U.S. Readiness Command. Composed of contingently assigned units from the United States Army, United States Air Force, United States Navy, and United States Marine Corps, its mandate was to rapidly deploy to confront worldwide threats to American interests.

  6. Mitochondrial antiviral-signaling protein - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_antiviral...

    [7] [8] [9] NF-κB, IRF1, and IRF3 are transcription factors and play critical roles in the production of cytokines. Cellular mechanisms of MAVS pathway. At a resting state for the cell, a protein called mitofusin 2 (MFN2) is known to interact with MAVS, preventing MAVS from binding to the cytosolic proteins, such as RIG-I and MDA5.

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    mail.aol.com

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  8. IRF4 - Wikipedia

    en.wikipedia.org/wiki/IRF4

    IRF4 is a transcription factor belonging to the Interferon Regulatory Factor (IRF) family of transcription factors. [8] [9] In contrast to some other IRF family members, IRF4 expression is not initiated by interferons; rather, IRF4 expression is promoted by a variety of bioactive stimuli, including antigen receptor engagement, lipopolysaccharide (LPS), IL-4, and CD40.

  9. IRF2 - Wikipedia

    en.wikipedia.org/wiki/IRF2

    IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation.