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Diabetic coma was a more significant diagnostic problem before the late 1970s, when glucose meters and rapid blood chemistry analyzers were not available in all hospitals. In modern medical practice, it rarely takes more than a few questions, a quick look, and a glucose meter to determine the cause of unconsciousness in a patient with diabetes.
Symptoms and effects can be mild, moderate or severe, depending on how low the glucose falls and a variety of other factors. It is rare but possible for diabetic hypoglycemia to result in brain damage or death. Indeed, an estimated 2–4% of deaths of people with type 1 diabetes mellitus have been attributed to hypoglycemia. [2] [3]
Diabetic coma is a medical emergency in which a person with diabetes mellitus is comatose (unconscious) because of one of the acute complications of diabetes: [24] [25] Severe diabetic hypoglycemia Diabetic ketoacidosis advanced enough to result in unconsciousness from a combination of severe hyperglycemia , dehydration and shock , and exhaustion
Diabetic ketoacidosis may be diagnosed when the combination of hyperglycemia (high blood sugars), ketones in the blood or on urinalysis and acidosis are demonstrated. [6] In about 10% of cases the blood sugar is not significantly elevated ("euglycemic diabetic ketoacidosis"). [3] A pH measurement is performed to detect acidosis.
In insulin-dependent diabetic patients this phenomenon is termed hypoglycemia unawareness and is a significant clinical problem when improved glycemic control is attempted. Another aspect of this phenomenon occurs in type I glycogenosis , when chronic hypoglycemia before diagnosis may be better tolerated than acute hypoglycemia after treatment ...
Central nervous system malformation - Malformations in the central nervous system such as septo-optic dysplasia, agenesis of corpus callosum, empty sella syndrome, and pituitary hypoplasia can cause central diabetes insipidus. [10] Brain death - Central diabetes insipidus is seen in roughly half of brain dead patients [21] [22] and is due to ...
In terms of mortality, hypoglycemia causes death in 6–10% of type 1 diabetics. [ 3 ] [ verification needed ] In those with type 2 diabetes , hypoglycemia is less common compared to type 1 diabetics , because medications that treat type 2 diabetes like metformin , glitazones , alpha-glucosidase inhibitors , glucagon-like peptide 1 agonists ...
Diabetic amyotrophy A disease of the nerves leading to the muscles. This condition affects only one side of the body and occurs most often in older men with mild diabetes. See also: Neuropathy. Diabetic angiopathy See: Angiopathy. Diabetic coma see coma Diabetic ketoacidosis (DKA) see acidosis Diabetic myelopathy