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Fifth disease, also known as erythema infectiosum and slapped cheek syndrome, [3] is a common and contagious disease caused by infection with parvovirus B19. [4] This virus was discovered in 1975 and can cause other diseases besides fifth disease. [5] Fifth disease typically presents as a rash and is most common in children.
Any area of the skin may be affected, with abdomen, legs, arms, neck, genital area, and face being the most common. [1] Onset of the lesions is around seven weeks after infection. [3] They usually go away within a year without scarring. [1] The infection is caused by a poxvirus called the molluscum contagiosum virus (MCV). [1]
This is a viral infection of the skin that usually presents in children ages 1–10 and immunocompromised patients. [12] The main symptom of this disease is round, hard, flesh colored, painless bumps, with sunken centers that are apparent on the surface of the skin (Figure 1).
It is the classic cause of the childhood rash called fifth disease or erythema infectiosum, or "slapped face syndrome". [5] [6] The name comes from it being the fifth in a list of historical classifications of common skin rash illnesses in children. [7] The virus was discovered by chance in 1975 by Australian virologist Yvonne Cossart.
Chronic scratching of lesions can cause thickening or lichenification of the skin or prurigo nodularis (generalized nodules that are severely itchy). [ 33 ] Another factor in the barrier failure and immunological dysregulation in people with atopic dermatitis may be due to decreases in tight junction protein Claudin-1 .
A skin infection is an infection of the skin in humans and other animals, that can also affect the associated soft tissues such as loose connective tissue and mucous membranes. [ citation needed ] They comprise a category of infections termed skin and skin structure infections (SSSIs), or skin and soft tissue infections (SSTIs), [ 1 ] and acute ...
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The area of skin involved can vary from small to covering the entire body. [1] [2] Dermatitis is also called eczema but the same term is often used for the most common type of skin inflammation, atopic dermatitis. [7] The exact cause of the condition is often unclear. [2] Cases may involve a combination of allergy and poor venous return. [1]