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CD68 immunostaining demonstrating macrophages and giant cells in a case of xanthogranulomatous pyelonephritis CD68 ( C luster of D ifferentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes , osteoclasts ), by circulating macrophages , and by tissue macrophages (e.g., Kupffer cells , microglia ).
Immunohistochemistry demonstrates that vascular endothelial cells are positive for Factor VIII, vimentin, CD31, and CD34 antibodies, [11] [12] but negative for Bcl-2 and HHV-8 antigens. [13] [14] Vimentin, Factor XIIIa, CD68, alpha-1-antitrypsin, and lysozyme are expressed by mononuclear cells, [11] [13] although neither S100 nor CD1a are. [12]
However, the term histiocyte has been used for multiple purposes in the past, and some cells called "histocytes" do not appear to derive from monocytic-macrophage lines. [3] The term Histiocyte can also simply refer to a cell from monocyte origin outside the blood system, such as in a tissue (as in rheumatoid arthritis as palisading histiocytes ...
Multinucleated giant cells due to an infection. H&E stain.. A giant cell (also known as a multinucleated giant cell, or multinucleate giant cell) is a mass formed by the union of several distinct cells (usually histiocytes), often forming a granuloma.
Vascular or multi-infarct dementia is a subcortical dementia in which people become slower (than) forgetful,” Segil said. “Early onset diabetes (increases) cardiovascular risk with an ...
Angiology (from Greek ἀγγεῖον, angeīon, "vessel"; and -λογία, -logia) is the medical specialty dedicated to studying the circulatory system and of the lymphatic system, i.e., arteries, veins and lymphatic vessels. [1] In the UK, this field is more often termed angiology, and in the United States the term vascular medicine is
Wendy Williams' health has taken a turn for the worse amid her battle with dementia and aphasia. The former "Wendy Williams Show" host, 60, has become "cognitively impaired and permanently ...
Vascular disease is a class of diseases of the vessels of the circulatory system in the body, including blood vessels – the arteries and veins, and the lymphatic vessels. Vascular disease is a subgroup of cardiovascular disease .