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Peritubular capillaries surround the cortical parts of the proximal and distal tubules, while the vasa recta go into the medulla to approach the loop of Henle. [1] [2] About one-fifth of the blood plasma is filtered into Bowman's capsule as the blood passes through the glomerular capillaries; four-fifths continues into the peritubular capillaries.
Whereas the peritubular capillaries surround the cortical parts of the tubules, the vasa recta go into the medulla and are closer to the loop of Henle, [1] [2] and leave to ascend to the cortex. [3] [4] Terminations of the vasa recta form the straight venules, branches from the plexuses at the apices of the medullary pyramids.
The loop of Henle is supplied by blood in a series of straight capillaries descending from the cortical efferent arterioles. These capillaries (called the vasa recta; recta is from the Latin for "straight") also have a countercurrent multiplier mechanism that prevents washout of solutes from the medulla, thereby maintaining the medullary ...
Note 3: The efferent arterioles do not directly drain into the interlobular vein, but rather they go to the peritubular capillaries first. The efferent arterioles of the juxtamedullary nephron drain into the vasa recta.
The interlobular arteries pass directly outward between the medullary rays to reach the fibrous tunic, where they end in the capillary network of this part. These vessels do not anastomose with each other, but form end-arteries. In their outward course, they give off lateral branches, which are the afferent arterioles that supply the renal ...
[1]: 22 Blood is filtered as it passes through three layers: the endothelial cells of the capillary wall, its basement membrane, and between the podocyte foot processes of the lining of the capsule. The tubule has adjacent peritubular capillaries that run between the descending and ascending portions of the tubule. [2]
The descending vasa recta, ascending vasa recta vessels, and the loop of Henle together form the countercurrent system of the kidney. In the afferent arteriole, blood is supplied at high pressure, which promotes filtration, and in the efferent arteriole, it is at low pressure, which promotes reabsorption .
This K + "leak" generates a positive electrochemical potential difference in the lumen. This drives more paracellular reabsorption of Na +, as well as other cations such as magnesium (Mg 2+) and importantly calcium Ca 2+ due to charge repulsion. This is also the part of the tubule that generates Tamm–Horsfall protein.