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  2. Ii antigen system - Wikipedia

    en.wikipedia.org/wiki/Ii_antigen_system

    The Ii antigen system is a human blood group system based upon a gene on chromosome 6 and consisting of the I antigen and the i antigen. [1] The I antigen is normally present on the cell membrane of red blood cells in all adults, while the i antigen is present in fetuses and newborns. [2]

  3. Template : Did you know nominations/Ii antigen system

    en.wikipedia.org/.../Ii_antigen_system

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  4. MHC class II - Wikipedia

    en.wikipedia.org/wiki/MHC_Class_II

    In some cells, antigens bind to recycled MHC class II molecules while they are in the early endosomes, while other cells such as dendritic cells internalize antigens via receptor-mediated endocytosis and create MHC class II molecules plus peptide in the endosomal-lysosomal antigen processing compartment which is independent of the synthesis of ...

  5. MHC multimer - Wikipedia

    en.wikipedia.org/wiki/MHC_multimer

    MHC pentamers have been used in the detection of antigen-specific CD8+ T cells in flow cytometry, [12] and are cited in over 750 peer reviewed publications , including several in the journals Nature [22] and Science. [23] [24] MHC pentamers can also be used in tissue staining, [25] and in magnetic isolation of antigen-specific T cells. [26]

  6. Antigen presentation - Wikipedia

    en.wikipedia.org/wiki/Antigen_presentation

    Peptide-MHC-II complexes (pMHC-II) are transported to the plasma membrane and the processed antigen is presented to the helper T cells in the lymph nodes. [ 9 ] APCs undergo a process of maturation while migrating, via chemotactic signals, to lymphoid tissues, in which they lose the phagocytic capacity and develop an increased ability to ...

  7. Antigen-presenting cell - Wikipedia

    en.wikipedia.org/wiki/Antigen-presenting_cell

    Professional APCs specialize in presenting antigens to T cells. [5] They are very efficient at internalizing antigens, either by phagocytosis (e.g. macrophages), or by receptor-mediated endocytosis (B cells), processing the antigen into peptide fragments and then displaying those peptides (bound to a class II MHC molecule) on their membrane. [1]

  8. Immunological memory - Wikipedia

    en.wikipedia.org/wiki/Immunological_memory

    Immunological memory is the ability of the immune system to quickly and specifically recognize an antigen that the body has previously encountered and initiate a corresponding immune response. Generally, they are secondary, tertiary and other subsequent immune responses to the same antigen.

  9. HLA-DQ - Wikipedia

    en.wikipedia.org/wiki/HLA-DQ

    HLA-DQ (DQ) is a cell surface receptor protein found on antigen-presenting cells.It is an αβ heterodimer of type MHC class II.The α and β chains are encoded by two loci, HLA-DQA1 and HLA-DQB1, that are adjacent to each other on chromosome band 6p21.3.