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About 9 in 10 of the people taking tirzepatide were able to maintain at least 80% of the weight they lost, while 17% of the placebo group maintained at least 80% of their weight loss.
When looking at specific weight loss thresholds, both men and women were far more likely to achieve reductions of 5%, 10%, and 15% body weight with tirzepatide compared to placebo.
About 82% of participants taking tirzepatide experienced 5% or greater weight loss. In comparison, only 66.5% of participants taking semaglutide achieved this level of weight loss. Which one to choose
Tirzepatide's efficacy for chronic weight management (weight reduction and maintenance) in combination with a reduced-calorie diet and increased physical activity was established in two randomized, double-blind, placebo-controlled trials of adults with obesity or overweight with at least one weight-related condition. [16]
According to an Eli Lilly-sponsored study, 10 to 15 milligrams of once-weekly tirzepatide can reduce appetite and food intake, both of which promote weight loss. 5. Metformin
In the early 2020s, GLP-1 receptor agonists such as semaglutide or tirzepatide became popular for weight loss because they are more effective than earlier drugs, causing a shortage for patients prescribed these medications for type 2 diabetes, their original indication.
A nother trial found tirzepatide helped overweight or obese patients without diabetes lose up to almost a quarter of their body weight, or 22%, after 17 months compared to a 2% weight loss with a ...
I was committed to my weight loss journey and set a goal to lose 60 pounds. My goal weight was 150 pounds, and I started on the lowest Mounjaro dose of 2.5 milligrams which was covered under my ...