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Flash freezing being used for cryopreservation. Flash freezing is used in the food industry to quickly freeze perishable food items (see frozen food). In this case, food items are subjected to temperatures well below [clarification needed] the freezing point of water. Thus, smaller ice crystals are formed, causing less damage to cell membranes. [3]
Cryogenic IQF freezers immerse the product in liquid nitrogen at very low temperatures, freezing it rapidly while continuously moving the product to avoid block or lump formation. [5] Although this method shows good freezing results, it might lead to higher processing costs per weight of product due to the cost of the liquid nitrogen required.
In this ice burn, the ice crystals that form have the potential to burn and scar the skin permanently. Blistering at the site of injury is common in more severe cases. [ 9 ] The freezing of tissue between the dermal and epidermal levels of the skin leads to a disruption in blood circulation, initially causing frost nip. [ 10 ]
Damage from freezing cold injury occurs through direct freezing of tissue, disrupted blood flow to affected skin, and rewarming injury. [ 8 ] [ 11 ] [ 3 ] Freezing causes ice crystal formation in tissue that disrupts cell membranes and surrounding blood vessels. [ 11 ]
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The pathological mechanism by which frostbite causes body tissue injury can be characterized by four stages: Prefreeze, freeze-thaw, vascular stasis, and the late ischemic stage. [16] Prefreeze phase: involves the cooling of tissues without ice crystal formation. [16] Freeze-thaw phase: ice-crystals form, resulting in cellular damage and death ...
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However, if contact with the aerosol is prolonged the skin will freeze further and deeper layers of tissue will be affected, causing a more serious burn that reaches the dermis, destroys nerves, and increases the risk of infection and scarring. [6] When the skin thaws, pain and severe discomfort can occur in the affected area. [7]