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It is commonly referred to as the main harmful PFAS chemical and PFOA is responsible for many of the negative health effects commonly associated with PFAS. Per- and polyfluoroalkyl substances are a group of synthetic organofluorine chemical compounds that have multiple fluorine atoms attached to an alkyl chain.
To learn more or to see if your children are eligible to participate in the PFAS-REACH Study, please email pfas-reach@silentspring.org, call/text 617-221-6428, or visit https://pfas-exchange.org ...
The monomers of such perfluoroalkoxy alkane polymers, in common with other per- and polyfluoroalkyl substances, are widespread in the environment due to human production and release of the chemicals; so durable that they are referred to as "forever chemicals"; and have detrimental health concerns not yet fully understood. [10]
2017 PFAS are on the Government of Canada's 2019 chart of substances prohibited by the Canadian Environmental Protection Act, 1999 (CEPA) and by the Prohibition of Certain Toxic Substances Regulations, 2012. These substances are under these regulations because they are "among the most harmful" and "have been declared toxic to the environment ...
In humans, PFHxS binds to blood albumin, [8] and relatively little PFHxS is found in the liver compared to longer chain PFASs such as PFOS. [9] The half-life of PFHxS in adult blood serum is 5.3 years (4.7 years for women and 7.4 years for men). [10] The half-life of PFASs in human blood generally decreases with decreasing backbone (CF 2) length.
The observed probable serious effects for human health and the environment are thyroid hormonal disturbances and reproductive toxicity seen in rodents, and effects on liver, kidney and haematological system in rats, hormonal disturbances and effects on reproduction in marine medaka fish and effects on expression of hormone receptors in tadpoles.
Perfluorooctanesulfonic acid (PFOS) (conjugate base perfluorooctanesulfonate) is a chemical compound having an eight-carbon fluorocarbon chain and a sulfonic acid functional group, and thus it is a perfluorosulfonic acid and a perfluoroalkyl substance (PFAS).
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